The ring at the open end of the female condom remains outside the vagina. Unlike latex — the material used to make most male condoms — female condoms are made of polyurethane and synthetic latex, which is safe for people who are allergic to natural rubber latex. The female condom can be used during anal sex, too. Insertion of a female condom To use a female condom, one ring is inserted into the vagina before sex to hold the condom in place. Product classification: Single-use internal condom. Food and Drug Administration. Female condoms aren't affected by dampness or changes in temperature. According to the FC2 website, the FC2 is reimbursable if you have insurance and a prescription from a doctor.