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Edition: Available editions United Kingdom. Confessions of a heterodox economist — Portsmouth, Hampshire. In addition to potential feelings of isolation and embarrassment, early puberty is linked to earlier sexual activity, which can lead to emotional damage as well as unwanted pregnancies and sexually transmitted diseases. ACKR2 stops the macrophages from moving into the breasts until the female is old enough, which prevents premature breast development. We found that mice that do not have ACKR2 start puberty early because the macrophage cells arrive in the breasts prematurely. Yet the higher risks of earlier developers ending up with breast cancer or the other diseases are a significant concern, not to mention other psychological and physical problems that can crop up. They do this by administering drugs that stop the pituitary glands from producing the hormones that trigger puberty. If so, it may be possible to predict early puberty by testing young children and boosting levels of the molecule to halt the process. Revising Pevsner — York, York.

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